• Endometrial adenocarcinoma invading the endocervix is histologically equivalent to cervical adenocarcinoma
  • Several benign conditions of the cervix can mimic adenocarcinoma
  • Cervical adenocarcinoma requires HPV infection; endometrial cancer is HPV negative
  • Thus, we interrogated several biomarkers associated with HPV infection to determine if they could differentiate endocervical from endometrial adenocarcinoma