Introduction:
- Endometrial adenocarcinoma invading the endocervix is histologically equivalent to cervical adenocarcinoma
- Several benign conditions of the cervix can mimic adenocarcinoma
- Cervical adenocarcinoma requires HPV infection; endometrial cancer is HPV negative
- Thus, we interrogated several biomarkers associated with HPV infection to determine if they could differentiate endocervical from endometrial adenocarcinoma