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SpecimenSeq™
and DTCs Matched Sets

Physiologically relevant, NGS-characterized dissociated tumor cells (DTCs) and matched sets.

Conduct smarter oncology R&D faster with SpecimenSeq™

SpecimenSeq bridges genetic and immunophenotypic biomarkers with clinical data to help you accelerate research and development of innovative precision oncology tools. 

The SpecimenSeq™ DTCs Inventory Report

SpecimenSeq™ DTCs and DTC matched sets are ideal for confirming biomarker targets, driver mutations, and clinically significant genomic variants. Discovery’s SpecimenSeq™ DTC inventory includes:

Do You Need Help Finding the Right Matched Sets?

Deliverables & Characterization

BIOSPECIMEN FORMAT CHARACTERIZATION REPORTS
DTCs
  • Clinical information and pathology report
  • Cell population analysis and HLA-A02 status by flow cytometry
  • HAD QGEN MultiModal service with QCI report
  • DTCs + PBMCS
  • Clinical information and pathology report
  • Cell population analysis and HLA-A02 status by flow cytometry (DTCs only)
  • HAD QGEN MultiModal service with QCI report (DTCs only)
  • DTCS + FFPE
  • Clinical information and pathology report
  • Cell population analysis and HLA-A02 status by flow cytometry (DTCs only)
  • HAD QGEN MultiModal service with QCI report (DTCs only)
  • DTCs + PBMCs + FFPE
  • Clinical information and pathology report
  • Cell population analysis and HLA-A02 status by flow cytometry (DTCs only)
  • HAD QGEN MultiModal service with QCI report (DTCs only)
  • NGS Characterization

    DNA GENE CONTENT (64 GENES)
    ABL1
    CDH1
    ER
    FLT3
    IDH2
    MLH1
    PDGFRA
    SMAD4
    AKT1
    CDKN2A
    ERBB2
    FOXL2
    JAK2
    MPL
    PIK3CA
    SMARCB1
    ALK
    CSF1R
    ERBB4
    GNA11
    JAK3
    MSH2
    PMS2
    SMO
    APC
    CTLA4
    EZH2
    GNAQ
    KDR
    MSH6
    PR
    SRC
    ATM
    CTNNB1
    FBXW7
    GNAS
    KIT
    MUM1
    PTEN
    STK11
    BCL6
    DDR2
    FGFR1
    HNF1A
    KRAS
    NOTCH1
    PTPN11
    TP53
    BRAF
    DNMT3A
    FGFR2
    HRAS
    MAP2K1
    NPM1
    RB1
    TSC1
    CD10
    EGFR
    FGFR3
    IDH1
    MET
    NRAS
    RET
    VHL
    RNA GENE FUSION CONTENT (6 PRIMARY GENES)
    EML4-ALK
    MPRIP-NTRK1
    NCOA4-RET
    GCC2-ALK
    SQSTM1-NTRK1
    TRIM33-RET
    HIP1-ALK
    TPR-NTRK1
    CD74-ROS1
    KIF5B-ALK
    TRIM24-NTRK2
    EZR-ROS1
    KLC1-ALK
    ETV6-NTRK3
    GOPC-RPS1
    STRN-ALK
    SQSTM1-NTRK3
    LRIG3-ROS1
    TFG-ALK
    CCDC6-RET
    SDC4-ROS1
    TPR-ALK
    CUX1-RET
    SLC34A2-ROS1
    CD74-NTRK1
    KIAA1217-RET
    TPM3-ROS1
    IRF2BP2-NTRK1
    KIF5B-RET

    NGS results are delivered via a Qiagen Clinical Insights (QCI) report that includes:

    Explore the Depths of Your Biospecimens

    Get biospecimens in the format you need – then characterize them with Discovery’s customizable and scalable biomarker services based on advanced technologies, including genomics, proteomics, molecular pathology, and cell biology services.

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