Discovery Fresh
Leukopaks™ (RUO)

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+2,800

highly characterized, 
recallable donors

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>98%

mononuclear cells in every leukopak

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< 48 hours

from collection to delivery

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~ 95%

viability of fresh leukopaks

Overview: Experience the confidence of Discovery Leukopaks™

Choosing Discovery means choosing confidence.

Phrases like single chain of custody, our own donor recruiting team, and in-house collection and processing facilities may not sound exciting, but the difference they make in the quality of our leukopaks is enormous. It’s all about the amount of insight and control we have from donor selection to shipped leukopak. Through small tweaks and optimizations at every stage of the process, we have built unparalleled excellence, reliability, and quality into our fresh leukopaks.

 

DOCUMENTATION:

RELATED PRODUCTS:

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DISCOVERY'S ADVANTAGES

Scalability

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We have 2,800+ recallable donors that can support your research with consistent materials.

Speed

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We can start collections within 2 – 14 days of receiving your purchase order, and provide same-day or next-day delivery, depending on your location.

Consistency

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We maintain a single chain of custody – from collection and leukapheresis to characterization and distribution of leukopaks to our clients. This affords consistent, rigorous quality control measures throughout and improves donor recallability via well-established donor relationships.

Continuity

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With the recent addition of our on-site GMP collection facility, you have the potential to use the same donors in research and clinical development/manufacturing, maximizing the efficiency and predictability of your operations.

Detailed 
donor Data

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In addition to the typical donor demographic information and infectious disease testing one would expect, we routinely HLA type all donors to 6-digit resolution using NGS.

Compliance

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We are FDA Licensed for Blood Products, GMP/GLP compliant, CLIA Registered and CAP registered with accreditation pending

Advanced Analysis and Cell Processing

The FDA licensed GMP Collection facility is housed in the same building as our Cell Processing, Flow Cytometry and our HudsonAlpha Discovery Genomics Center, which provides highly sophisticated analyses and high quality data meeting our customers’ turnaround time needs.

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CONSULTATIVE CELL SERVICES

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READY FOR GMP-GRADE LEUKOPAKS?

Product
Details

Discovery Fresh Leukopaks are manufactured from the peripheral blood of normal human donors at our wholly owned and operated US Donor Center. Each Discovery Fresh Leukopak consists of a concentrated fraction of mononuclear cells including:

EACH DISCOVERY CRYO LEUKOPAK (RUO) CONSISTS OF A CONCENTRATED FRACTION OF MONONUCLEAR CELLS INCLUDING:

  • B cells
  • Dendritic cells
  • T cells
  • Monocytes
  • NK cells
  • CD34+

All cells are obtained using IRB approved consent forms and protocols. Each donor is tested for HIV, HBV, HCV, and CMV, and HLA typed via 6-digit NGS. Additional characterization can be performed—please inquire.

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RESEARCH USE ONLY. NOT INTENDED FOR CLINICAL USE.

Discovery Fresh Leukopaks (RUO)Product No.Total Cell CountList Price*

Full Leukopak

780239.5 Billion Minimum$3,120
Half Leukopak536785 Billion Minimum$2,080
Quarter Leukopak756632.5 Billon Minimum$1,716
Custom OrderC-5672CustomContact Us for Pricing

* Pricing may vary depending on your project specific details. Contact us for project specific pricing.

Donor Information

All cells are obtained using IRB approved consent forms and protocols. 
We perform extensive characterization of all donors that includes:

Demographic Information

  • Age
  • Height
  • Sex
  • Smoking status
  • Ethnicity
  • Blood type
  • Weight

HLA-typing to 6-digit resolution with NGS

Virus Testing Every 90 Days

  • Hepatitis B Core Antibody (Anti-HBc EIA)
  • Hepatitis C Virus Antibody (Anti-HCV EIA)
  • Human Immunodeficiency Virus Antibody (HIV 1/2 plus O)
  • Additional tests can be performed—please inquire.

Example of a

Certificate 
of Analysis

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Technical Resources

Related Products & Services:

Discovery Life Sciences also offers GMP compliant Discovery Fresh Leukopaks, Discovery Fresh Leukopaks™ (RUO) and cryopreserved, primary immune cell isolates which are produced from Discovery Fresh Leukopaks, with the ability to begin all cell isolation protocols within 1 hour of leukapheresis.

Learn More

Frequently Asked Questions

Where are your sites?
Our Research Use Only (“RUO”) and our Good Manufacturing Processes (“GMP”) collections are both done in Huntsville, AL, in two separate suites in the same building. Our Cell Biology Lab is also co-located in the same facility, enabling real-time fresh processing or downstream manipulation as needed.
Your samples are all from healthy, normal donors—how do you define “normal"?

For a donor to qualify as normal, they cannot be currently diagnosed or have a history of cancer, autoimmune disease, or any major comorbidity (i.e. diabetes, high blood pressure, etc.). Contact us to learn more.

Can I follow the same donor from RUO to GMP?
Yes. Discovery Life Sciences owns and controls our entire supply chain from donor recruitment, donor screening, donor collection, and logistics to the end user. As a result, our operations are highly efficient and we can ensure a good relationship with our donors, with many returning again and again. Thus, you have the potential to use the same donor from RUO (Research Use Only) collections to GMP compliant collections for clinical use.
Has COVID-19 affected your collection, processing, and/or analytical facilities?
Our collection clinic, cell processing, NGS, and flow cytometry facilities have not been negatively impacted by COVID-19. We are located in Huntsville, Alabama, and have been considered an essential business by the state, enabling our facilities to remain open and fully operational. In addition, we have been able to continuously maintain our supply chain for lab consumables, keeping all projects running on schedule.
How often can you perform apheresis on a specific donor?
There must be a 61 day delay between one leukopheresis to the next donation. In addition, we require that our donors wait 21 days after a standard venipuncture (whole blood collection) before donating a leukopheresis product.
What anticoagulant do you use for Discovery Leukopaks™?
We use ACD-A.
Which collection protocol/program and consumable sets are you using?
We use the CMNC (Continuous Mononuclear Cells) Protocol. This allows us to use only one separation process which is far more efficient than the MNC Protocol.

To propel your projects with The Power of Discovery.™

Contact Us Today

Let us know about your project!

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