Matched sample sets of human biospecimens collected from the same patient and time point are a critical component to many important research investigations. For example, matched FFPE and plasma sample sets are imperative for liquid biopsy assays, while DTCs and PBMCs are key for immune repertoire analysis. Discovery is pleased to support ground breaking research projects by providing a range of high-quality matched sample sets.
Discovery offers the full spectrum of human matched sample sets. Our inventory boasts a range of commonly requested sample sets, many with deep genomic characterization. Additionally, our Discovery Partners® network allows for large-scale, prospective collections. Each matched sample set is provided with the base clinical data from the patient case, along with redacted pathology information. Our scientific team has the knowledge and technical capacity to meet custom requirements and offer laboratory services for matched sample set projects.
Characterized samples sets are now available and include clinically relevant mutations and biomarkers, such as: EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF. See the chart below for indication specifics.
Sophisticated technologies and resourceful scientists are available to accelerate projects timelines.
Laboratory services related to matched samples include:
| Test | Method | Lung | Colon | Gastric | Mel. | H&N | Panc. | Cervical | Bladder | Renal |
|---|---|---|---|---|---|---|---|---|---|---|
| EGFR | PCR | Y | N | N | N | N | N | N | N | N |
| PD-L1 | IHC | Y | N | N | Y | Y | N | N | Y | Y |
| KRAS | PCR | Y | Y | N | N | N | Y | N | N | N |
| NRAS | PCR | Y | Y | N | Y | Y | Y | N | N | N |
| MSI | PCR | N | Y | Y | N | N | N | Y | N | N |
| MMR | IHC | N | Y | Y | N | N | N | Y | N | N |
| BRAF | PCR | N | Y | N | Y | N | N | N | N | N |
| HPV | PCR | N | N | Y | N | Y | N | Y | N | N |
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