Overview:

Experience the confidence of Discovery Leukopaks

Phrases like single chain of custody, our own donor recruiting team, and in-house collection and processing facilities may not sound exciting, but the difference they make in the quality of our leukopaks is enormous. It’s all about the amount of insight and control we have from donor selection to shipped leukopak. Through small tweaks and optimizations at every stage of the process, we have built unparalleled excellence, reliability, and quality into our fresh leukopaks. This is why whether you’re looking for a reliable source of high-quality human primary immune cells for basic or translational research, such as for cell or gene therapy development, diagnostic test development, disease-state studies, and more…

Choosing Discovery means choosing confidence.

Discovery’s Advantages

Scalability

We have 2,800+ recallable donors that can support your research with consistent materials.

Speed

We can start collections within 2 – 14 days of receiving your purchase order, and provide same-day or next-day delivery, depending on your location.

Consistency

We maintain a single chain of custody – from collection and leukapheresis to characterization and distribution of leukopaks to our clients. This affords consistent, rigorous quality control measures throughout and improves donor recallability via well-established donor relationships.

Continuity

With the recent addition of our on-site GMP collection facility, you have the potential to use the same donors in research and clinical development/manufacturing, maximizing the efficiency and predictability of your operations.

Detailed donor characterization

In addition to the typical donor demographic information and infectious disease testing one would expect, we routinely HLA type all donors to 6-digit resolution using NGS.

Compliance

We are FDA Licensed for Blood Products, GMP/GLP compliant, CLIA Registered and CAP registered with accreditation pending

Advanced analysis and cell processing

The FDA licensed GMP Collection facility is housed in the same building as our Cell Processing, Flow Cytometry and our HudsonAlpha Discovery Genomics Center, which provides highly sophisticated analyses and high quality data meeting our customers’ turnaround time needs

Consultative Cell Services
Learn More
Ready for GMP-grade leukopaks?
Get Started

+2,800

Highly characterized, recallable donors

~95%

mononuclear cells in every leukopak

<48 hours

from collection to delivery

>98%

viability of fresh leukopaks

Detailed information

Discovery Fresh Leukopaks are manufactured from the peripheral blood of normal human donors at our wholly owned and operated US Donor Center. Each Discovery Fresh Leukopak consists of a concentrated fraction of mononuclear cells including:

Each Discovery Cryo Leukopak (RUO) consists of a concentrated fraction of mononuclear cells including:
  • B cells
  • T cells
  • NK cells
  • Dendritic cells
  • Monocytes
  • CD34+

All cells are obtained using IRB approved consent forms and protocols. Each donor is tested for HIV, HBV, HCV, and CMV, and HLA typed via 6-digit NGS.

Download an example report

Additional characterization can be performed— please inquire.

Immune Cell Populations in Discovery Leukopaks

Research Use Only. Not Intended for clinical use.

Discovery Fresh Leukopaks (RUO)Product No.Total Cell CountList Price*
Full Leukopak780239.5 Billion Minimum$3,000
Half Leukopak536785 Billion Minimum$2,000
Quarter Leukopak756632.5 Billion Minimum$1,650
Custom OrderC-5672CustomContact Us for Pricing

* Pricing may vary depending on your project specific details. Contact us for project specific pricing.

Donor information

All cells are obtained using IRB approved consent forms and protocols. We perform extensive characterization of all donors that includes:

Demographic information
  • Age
  • Height
  • Sex
  • Smoking status
  • Ethnicity
  • Blood type
  • Weight
HLA-typing to 6-digit resolution with NGS
Virus testing every 90 days
  • Hepatitis B Core Antibody (Anti-HBc EIA)
  • Hepatitis C Virus Antibody (Anti-HCV EIA)
  • Human Immunodeficiency Virus Antibody (HIV 1/2 plus O)
  • Additional tests can be performed— please inquire.

Frequently Asked Questions

Where are your sites?

Our Research Use Only (“RUO”) and our Good Manufacturing Processes (“GMP”) collections are both done in Huntsville, AL, in two separate suites in the same building. Our Cell Biology Lab is also co-located in the same facility, enabling real-time fresh processing or downstream manipulation as needed.

Your samples are all from healthy, normal donors—how do you define “normal"?

For a donor to qualify as normal, they cannot be currently diagnosed or have a history of cancer, autoimmune disease, or any major comorbidity (i.e. diabetes, high blood pressure, etc.). Contact us to learn more.

Can I follow the same donor from RUO to GMP?

Yes. Discovery Life Sciences owns and controls our entire supply chain from donor recruitment, donor screening, donor collection, and logistics to the end user. As a result, our operations are highly efficient and we can ensure a good relationship with our donors, with many returning again and again. Thus, you have the potential to use the same donor from RUO (Research Use Only) collections to GMP compliant collections for clinical use.

Has COVID-19 affected your collection, processing, and/or analytical facilities?

Our collection clinic, cell processing, NGS, and flow cytometry facilities have not been negatively impacted by COVID-19. We are located in Huntsville, Alabama, and have been considered an essential business by the state, enabling our facilities to remain open and fully operational. In addition, we have been able to continuously maintain our supply chain for lab consumables, keeping all projects running on schedule.

What apheresis equipment do you use?

We use Spectra Optia apheresis machines.

Which collection protocol/program and consumable sets are you using?

We use the CMNC (Continuous Mononuclear Cells) Protocol. This allows us to use only one separation process which is far more efficient than the MNC Protocol.

How often can you perform apheresis on a specific donor?

There must be a 61 day delay between one leukopheresis to the next donation. In addition, we require that our donors wait 21 days after a standard venipuncture (whole blood collection) before donating a leukopheresis product.

A Primer on Human PBMCs

A quick reference resource for scientists who need to isolate, manipulate or develop assays involving human mononuclear cells.

Get the FREE e-book

Place your order or request project specific quote

Questions? Call our Customer Service Team at 1 (866) 838-2798.