Human Tissue Sample Blog

PIK3CA: Explaining the Oncogene

Posted by Quinton Stevens on Jan 31, 2017 3:20:00 PM

    

 

Introduction

Cancer is a disease that comes from normal cells dividing and mutating abnormally. Often with cancer there is a specific genetic defect that causes the disease, and one, in particular, has been connected to colon cancer, gastric cancer, breast cancer, endometrial cancer, lung cancer and gliomas.

This defect is a mutation of the PIK3CA gene. This gene is responsible for a plethora of administrative tasks in each cell. These tasks range from the ability to intake nutrients, survival, cell differentiation, cell reproduction, and cell growth. Naturally, such an important gene’s failure is a serious problem that often results in a cell simply dying. In the case of some mutations, however, the cell can carry on and become cancerous. It’s this type of outcome scientists hope to learn more about in the near future.

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