Science

Matched sample sets of human biospecimens collected from the same patient and time point are a critical component to many important research investigations. For example, matched FFPE and plasma sample sets are imperative for liquid biopsy assays, while DTCs and PBMCs are key for immune repertoire analysis. Discovery is pleased to support ground breaking research projects by providing a range of high-quality matched sample sets. 

SERVICE

Discovery offers the full spectrum of human matched sample sets. Our inventory boasts a range of commonly requested sample sets, many with deep genomic characterization. Additionally, our Discovery Partners® network allows for large-scale, prospective collections. Each matched sample set is provided with the base clinical data from the patient case, along with redacted pathology information. Our scientific team has the knowledge and technical capacity to meet custom requirements and offer laboratory services for matched sample set projects.

Characterized samples sets are now available and include clinically relevant mutations and biomarkers, such as:  EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF. See the chart below for indication specifics.

Sample Sets and Inventory Available:

*Please note that many of these inventory reports contain multiple tabs.

  • DTCs + PBMCs  - may include cell population analysis of DTCs by flow cytometry and may include: EGFR, KRAS, NRAS, MSI, and BRAF
  • FFPE + Plasma  - may include: EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF
  • FFPE + Plasma + Buffy Coat - may include: EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF
  • FFPE + DTCs - may include: EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF
  • FFPE + DTCs + PBMCsincludes cell population analysis of DTCs by flow cytometry and may include: EGFR, PD-L1, KRAS, NRAS, MSI, MMR, and BRAF
  • FFPE + DTCs + PBMCs + Buccal Swab   - inquire below if these sets are of interest.
  • FFPE tumor + FFPE normal adjacent tissue   - inquire below if these sets are of interest.

Biomarkers Available by Indication:

Test Method Lung Colon Gastric Mel. H&N Panc. Cervical Bladder Renal
EGFR PCR Y N N N N N N N N
PD-L1 IHC Y N N Y Y N N Y Y
KRAS PCR Y Y N N N Y N N N
NRAS PCR Y Y N Y Y Y N N N
MSI PCR N Y Y N N N Y N N
MMR IHC N Y Y N N N Y N N
BRAF PCR N Y N Y N N N N N
HPV PCR N N Y N Y N Y N N
 
 
 
 
 
 
 
 
 
Related Services:

Sophisticated technologies and resourceful scientists are available to  accelerate projects timelines. Laboratory services related to matched samples include:


Connect With Us:

Submit this form to start a conversation with Discovery to:

  • Begin a matched sample sets purchase
  • Discuss a custom project
  • Ask questions about our biospecimens