Biomarker Services

Discovery’s expert multi-omic biomarker testing services are optimized for speed and large scale capacity. Our global biomarker service laboratories routinely manage hundreds of global studies and expertly test thousands of biospecimens simultaneously using NGS, IHC, flow cytometry and other technologies.

Gain Deeper Insights and Preserve Precious Samples Through Discovery's Integrated Multi-omic Biomarker Services

Discovery Life Sciences offers a wide range of integrated, scalable biomarker services, including genomics, proteomics, molecular pathology, and cell biology.  The same sample can be simultaneously tested in different workflows producing high-quality data in less time and preserving precious clinical samples.

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A WORLD-CLASS GENOMIC SERVICES LAB WITH INDUSTRIAL-SCALE CAPABILITIES

Genomic Biomarkers

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Whole Genome Sequencing

Scalable whole genome sequencing services with the coverage and quality to meet your project needs.

  • Including tumor percentage, tumor enriched area, 4-micron sections, etc.
  • Molecular pathology results included where available

Targeted & Exome
Sequencing

Multiple options for coverage, targeted sequencing panels, and capture platforms enable basic, translational, and clinical studies.

  • IDT, Twist, Agilent capture platforms
  • 50x, 100x, 300x, and custom coverage
  • Illumina TruSight panels

RNA-SEQ

Proprietary isolation protocols deliver high quality RNA even from difficult samples.

  • Multiple RNA types, including mRNA, long non-coding RNA, miRNA, regulatory RNAs, exosomal RNA
  • Robust RNA isolation from FFPE tissue
  • Multiple RNA amplification and library construction methods from both low and high quality RNA

HiFi Long Sequencing

Advance your oncology, neurology, viral and other rare disease research by uncovering complex drivers of disease with Discovery’s long-read, next generation sequencing services (LRS)

  • Identify biologically significant structural variants
  • Identify RNA splice site isoforms from cDNA
  • Gain insight into difficult to sequence regions of the genome

Single Cell Sequencing

Improve the resolution of your genomic data with single cell sequencing

  • 10x, Genomics technologies
  • 30x, 60x, 90x, custom RNA-Seq, TCR-Seq, BCR-Seq, CITE-Seq, and ATAC-Seq
  • 10x Genomics Cell Ranger Analysis
  • Qualitative and quantitative analyses

Epigenomics

Advance insight into epigenetic regulation of gene expression

  • Illumina’s Infinium
    MethylationEPIC BeadChip (850K sites) technology
  • ATAC-Seq with 10x
    Genomics technology
  • Next generation sequencing (NGS) of bisulfite-treated libraries

Metagenomics

Explore the microbiome with a range of metagenomic sequencing services.

  • Nucleic acid extraction from
    environmental and clinical samples
  • Whole genome shotgun
    metagenomics
  • Meta-transcriptomic
    sequencing
  • 16S rRNA sequencing

Scalable HiFi Sequencing Services 

Webinar With PacBio

POWER YOUR PRECISION BIOMARKER PROGRAMS WITH PATHOLOGY GUIDED TISSUE BIOMARKER SERVICES

Tissue Biomarker Services

Make strategic decisions with confidence. Our experts help you identify and understand biomarkers within your target populations at every stage of research and clinical development – from assay development and validation to clinical trial support.

High Quality IHC Services Fit for
Any Stage of Research & Development

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Preclinical and
Translational Studies

We apply expert knowledge of fundamental biological processes to understand targets in preclinical models and accelerate transition to the next stage of development

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Assay Development

Our experts start with the end in mind to tailor assays for the right targets in the right patients on the right platforms

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Assay Validation

Expert determination and optimization of assay performance

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Target Expression

Unique integrated biospecimen and expert multi-omic services - flow cytometry, ELISA, sequencing and IHC - enable a thorough understanding of target expression.

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Global Clinical Trial Services

Get high quality results at speed and scale to accelerate global clinical trials using a single chain of custody that adheres to all appropriate regulations and quality standards

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Companion Diagnostics

Leverage the expertise behind one of the most successful companion diagnostic on the market to advance your companion diagnostic programs

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Discovery Biomarker Academy

Accelerate adoption postmarket with expert training for pathologists and technicians

Leverage Discovery’s expert cell-based services to conduct targeted immunophenotyping, functional and other cell-based studies and analyses.

Cell Services

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Custom
Biospecimen
Processing Services

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Get the biospecimens
you want in the
formats you need.

We help you optimize biospecimen utility for your specific applications by expertly executing cellular processing, FACS, magnetic isolations, and custom sample preparations for diseased and normal tissues, tumors, blood and other sample types. 

 
 
 
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Flow Cytometry Services

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Understand phenotypic and functional biomarkers.

We help you understand the phenotypic and functional biomarkers in your cohorts by delivering accurate multiparametric flow cytometry data using standard and customized panels that interrogate diseased and normal whole blood, primary cells, fresh or frozen PBMCs, cell lines, normal tissues and their cellular subsets.

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In Vitro Cell
Culture Services

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Inform downstream
studies by evaluating
in vitro cellular changes.

Our cell biology experts can perform primary cell cultures services derived from human blood and tissue with multiple analytical readouts, so you can understand growth characteristics, phenotypic changes, cytotoxicity, immune cell proliferation / expansion / differentiation, and drug response (including effector cell platforms) to inform and accelerate development.

 
 
 
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10x Single Cell Services

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Improve the resolution of genomic data

We help you understand the status of individual cells as a 10X Chromium Certified Service Provider. Our expert cell biologists perform single-cell sequencing library preparation, including specialized sample preparation, multiple QC checks throughout library construction, and pipeline data analysis. Our genomic biomarker experts in our sequencing and bioinformatics service laboratory, HudsonAlpha Discovery, then takeover to conduct a wide variety of single cell sequencing services.

 

DISCOVERY IS A GLOBAL MARKET LEADER IN BIOSPECIMEN ANALYSIS, PROCUREMENT, AND DISTRIBUTION FOR PHARMACEUTICAL, BIOTECHNOLOGY, AND DIAGNOSTICS INDUSTRIES.

Need biospecimens to build your study cohorts?

Discovery offers a full spectrum of biospecimen solutions for diseased patients and healthy donors. From small and simple projects to complex prospective studies, Discovery has the expertise, inventory and global clinical networks to meet your biospecimen needs.

To propel your projects with The Power of Discovery.™

Contact Us Today

Let us know about your project!

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