Gain Deeper Insights and Preserve Precious Samples Through Discovery's Integrated Multi-omic Biomarker Services
Discovery Life Sciences offers a wide range of integrated, scalable biomarker services, including genomics, proteomics, molecular pathology, and cell biology. The same sample can be simultaneously tested in different workflows producing high-quality data in less time and preserving precious clinical samples.
A WORLD-CLASS GENOMIC SERVICES LAB WITH INDUSTRIAL-SCALE CAPABILITIES
Genomic Biomarkers
Whole Genome Sequencing
Scalable whole genome sequencing services with the coverage and quality to meet your project needs.
- Including tumor percentage, tumor enriched area, 4-micron sections, etc.
- Molecular pathology results included where available
Targeted & Exome
Sequencing
Multiple options for coverage, targeted sequencing panels, and capture platforms enable basic, translational, and clinical studies.
- IDT, Twist, Agilent capture platforms
- 50x, 100x, 300x, and custom coverage
- Illumina TruSight panels
RNA-SEQ
Proprietary isolation protocols deliver high quality RNA even from difficult samples.
- Multiple RNA types, including mRNA, long non-coding RNA, miRNA, regulatory RNAs, exosomal RNA
- Robust RNA isolation from FFPE tissue
- Multiple RNA amplification and library construction methods from both low and high quality RNA
HiFi Long Sequencing
Advance your oncology, neurology, viral and other rare disease research by uncovering complex drivers of disease with Discovery’s long-read, next generation sequencing services (LRS)
- Identify biologically significant structural variants
- Identify RNA splice site isoforms from cDNA
- Gain insight into difficult to sequence regions of the genome
Single Cell Sequencing
Improve the resolution of your genomic data with single cell sequencing
- 10x, Genomics technologies
- 30x, 60x, 90x, custom RNA-Seq, TCR-Seq, BCR-Seq, CITE-Seq, and ATAC-Seq
- 10x Genomics Cell Ranger Analysis
- Qualitative and quantitative analyses
Epigenomics
Advance insight into epigenetic regulation of gene expression
- Illumina’s Infinium
MethylationEPIC BeadChip (850K sites) technology - ATAC-Seq with 10x
Genomics technology - Next generation sequencing (NGS) of bisulfite-treated libraries
Metagenomics
Explore the microbiome with a range of metagenomic sequencing services.
- Nucleic acid extraction from
environmental and clinical samples - Whole genome shotgun
metagenomics - Meta-transcriptomic
sequencing - 16S rRNA sequencing
Scalable HiFi Sequencing Services
Webinar With PacBio
POWER YOUR PRECISION BIOMARKER PROGRAMS WITH PATHOLOGY GUIDED TISSUE BIOMARKER SERVICES
Tissue Biomarker Services
Make strategic decisions with confidence. Our experts help you identify and understand biomarkers within your target populations at every stage of research and clinical development – from assay development and validation to clinical trial support.
High Quality IHC Services Fit for
Any Stage of Research & Development
Preclinical and
Translational Studies
We apply expert knowledge of fundamental biological processes to understand targets in preclinical models and accelerate transition to the next stage of development
Assay Development
Our experts start with the end in mind to tailor assays for the right targets in the right patients on the right platforms
Assay Validation
Expert determination and optimization of assay performance
Target Expression
Unique integrated biospecimen and expert multi-omic services - flow cytometry, ELISA, sequencing and IHC - enable a thorough understanding of target expression.
Global Clinical Trial Services
Get high quality results at speed and scale to accelerate global clinical trials using a single chain of custody that adheres to all appropriate regulations and quality standards
Companion Diagnostics
Leverage the expertise behind one of the most successful companion diagnostic on the market to advance your companion diagnostic programs
Discovery Biomarker Academy
Accelerate adoption postmarket with expert training for pathologists and technicians
Leverage Discovery’s expert cell-based services to conduct targeted immunophenotyping, functional and other cell-based studies and analyses.
Cell Services
Custom
Biospecimen
Processing Services
Get the biospecimens
you want in the
formats you need.
We help you optimize biospecimen utility for your specific applications by expertly executing cellular processing, FACS, magnetic isolations, and custom sample preparations for diseased and normal tissues, tumors, blood and other sample types.
Flow Cytometry Services
Understand phenotypic and functional biomarkers.
We help you understand the phenotypic and functional biomarkers in your cohorts by delivering accurate multiparametric flow cytometry data using standard and customized panels that interrogate diseased and normal whole blood, primary cells, fresh or frozen PBMCs, cell lines, normal tissues and their cellular subsets.
In Vitro Cell
Culture Services
Inform downstream
studies by evaluating
in vitro cellular changes.
Our cell biology experts can perform primary cell cultures services derived from human blood and tissue with multiple analytical readouts, so you can understand growth characteristics, phenotypic changes, cytotoxicity, immune cell proliferation / expansion / differentiation, and drug response (including effector cell platforms) to inform and accelerate development.
10x Single Cell Services
Improve the resolution of genomic data
We help you understand the status of individual cells as a 10X Chromium Certified Service Provider. Our expert cell biologists perform single-cell sequencing library preparation, including specialized sample preparation, multiple QC checks throughout library construction, and pipeline data analysis. Our genomic biomarker experts in our sequencing and bioinformatics service laboratory, HudsonAlpha Discovery, then takeover to conduct a wide variety of single cell sequencing services.
DISCOVERY IS A GLOBAL MARKET LEADER IN BIOSPECIMEN ANALYSIS, PROCUREMENT, AND DISTRIBUTION FOR PHARMACEUTICAL, BIOTECHNOLOGY, AND DIAGNOSTICS INDUSTRIES.
Need biospecimens to build your study cohorts?
Discovery offers a full spectrum of biospecimen solutions for diseased patients and healthy donors. From small and simple projects to complex prospective studies, Discovery has the expertise, inventory and global clinical networks to meet your biospecimen needs.
To propel your projects with The Power of Discovery.™
Contact Us Today
Let us know about your project!
